Improving protein-protein interaction prediction using evolutionary information from low-quality MSAs
نویسندگان
چکیده
منابع مشابه
Improving protein-protein interaction prediction using evolutionary information from low-quality MSAs
Evolutionary information stored in multiple sequence alignments (MSAs) has been used to identify the interaction interface of protein complexes, by measuring either co-conservation or co-mutation of amino acid residues across the interface. Recently, maximum entropy related correlated mutation measures (CMMs) such as direct information, decoupling direct from indirect interactions, have been de...
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ژورنال
عنوان ژورنال: PLOS ONE
سال: 2017
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0169356